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Title   Hodgkin 씨 병에 대한 Cyclophosphamide , Vincristine , Procarbazine , Prednisone ( C - MOPP ) 4 제 복합화학요법의 치료효과 ( Combination Chemotherapy with Cyclophosphamide , Vincristine , Procarbazine , Prednisone ( C - MOPP ) in Hodgkin's Disease )
Publicationinfo   1991 Jan; 023(04): 806-814.
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Abstract   Between November 1977 and December 1987, the combination chemotherapy with cyclophosphamide, vincristine, procarbazine, and Prednisone (C-MOPP) had been administered in 29 patients with stage III-IV Hodgkins disease or recurrent cases after radiotherapy. Among 28 evaluable patients, 20 patients(71.4%) achieved complete responses and 8 patients(28.6%) had partial reaponses. The overall 5-year survival rate was 50.3% and the 5-year disease-free survi- val of complete responders was 55.7%. The frequent nonhematologic toxicties(WHO criteria grade>=II) were alopecia(96.4%) and nausea/vomiting(42.8%) but hematologic toxicities were minimal. In conclusion, C-MOPP regimen was effective and well tolerated for the treatment of stage III-IV and recurrent Hodgkins disease.
저 자   정경해(Kyung Hae Jung),신동복(Dong Bok Shin),김현아(Hyun Ah Kim),박영이(Young Iee Park),김태유(Tae You Kim),박근칠(Keun Chil Park),강윤구(Keun Chil Park),허대석(Dae Seog Heo),방영주(Yung Jue Bang),김노경(Noe Kyeong Kim)